Psilocybe Cubensis, Magic mushrooms

Psilocybe cubensis (Magic Mushrooms) is probably the best known of all the hallucinogenic mushrooms, also known as magic mushrooms. Its major psychoactive compounds are:

* Psilocybin
* Psilocin
* Baeocystin
* Norbaeocystin

Psilocin and psilocybin is found in the whole mushroom, in the cap and in the stem.

Determining the appropriate dose is not easy, for a modest psychedelic effect, a minimum of one gram of dried Psilocybe cubensis mushrooms is ingested orally. half a gram to one gram is usually sufficient to produce a mild effect, one or two grams usually provides a moderate effect. three or more grams usually produces strong effects. For most people, three dried grams would be considered a high dose and may produce an intense experience although, typically this is considered a standard dose. For many individuals doses above three grams may be overwhelming.

Due to factors such as age and storage method, the psilocybin content of a given sample of mushrooms will vary.

Effects usually start after approximately half an hour to one hour, depending on method of ingestion and stomach contents and may last from four to ten hours, depending on dosage. Visual distortions often occur, including walls that seem to breathe, a vivid enhancement of colors and the animation of organic shapes. At higher doses, experiences tend to be less social and more entheogenic, often intense and spiritual in nature.

It is nearly impossible to overdose on psilocybin mushrooms since one would have to consume several dozen pounds of fresh mushrooms. Nevertheless, the effects of very high doses can be overwhelming depending on the particular strain, growth method, age at harvest and the individual. Psilocybe cubensis mushrooms can come in rather different sizes. It is recommended that one weigh the actual mushrooms, as opposed to simply counting them. People taking MAOIs need to be careful, as psilocybin and psilocin are metabolized by the enzyme monoamine oxidase. A monoamine oxidase inhibitor reduces the body's ability to metabolize psilocin and psilocybin, greatly increasing the intensity of the experience. This can sometimes produce uncomfortable or undesirably intense experiences.